Research
A scientific setting for targeted research and trial support
Our facilities grew out of the 1987 Cambridge-NARIP® project on regulated exocytosis. The monitoring technology that came from that work led to papers in Nature (Lledo et al., 1993) and Nature Protocols (Rituper et al., 2013).
Collaboration
The team works closely with the Molecular Cell Physiology Lab at the University of Ljubljana on single-cell function and subcellular organelle physiology.
Methods
Methods
- Confocal and super-resolution microscopy (Elyra platform)
- Electrophysiology and capacitance measurements (Cambridge-NARIP®)
- Cytosolic calcium, cAMP, glucose, lactate and citrate assays
- Molecular biology methods
- In-house software: Particle TR, Particle CO, ColocANA, CELL
Carl Zeiss reference centre
Carl Zeiss reference centre
Since 2006 we have run a Carl Zeiss Reference Centre for Confocal Microscopy with two LSM510 microscopes (one with a Faraday cage, one with a Meta PMT array detector).
Confocal microscopy centre